Thursday

- Afternoon

Arrival by chartered bus from Nancy

Note: For people coming directly to Bischenberg, we will organize transportation from the airport and the train station during the afternoon and evening. Please communicate your arrival and departure times and places.

Registration

- Evening: Mixer

Friday

- Morning

1) 09:00 - 10:30 : High resolution. Methodology

09:00 – 09:30 Keith Wilson
Protein Crystallography at Atomic Resolution

09:30 – 09:50 Raul Cachau

The New – Old chemistry of proteins at ultra-high resolution

09:50 – 10:10 Isabelle Uson

Ab initio dual space recycling [sub]structure solution

10:10–10.30 Carlos Frazao

Ab initio structure determination of high resolution diffracting macromolecules

2) 11:00-12:30 : High resolution. Results 1

11:00 – 11:30 Victor Lamzin

(Title not communicated)

11:30 – 12:00 Pedro Alzari
Atomic resolution studies of endoglucanase CelA Clostridium thermocellum

12:00 – 12:30 Alberto Podjarny

The structure of an Aldose Reductase -Inhibitor complex (36 KDaltons) at 0.66 Å resolution

 

- Afternoon

3) 15:00-16:30 : High resolution Results 2

15:00 – 15:20 Bruno Klaholz

CH…O hydrogen bonds as a discrimination tool for drug selectivity: ligand complexes of the retinoic acid nuclear receptor at 1.4 Å resolution.

15:20 – 15:40 Anabelle Varrot

Snapshot along the retaining mechanism at atomic resolution.

15:40 – 16:00 Claude Lecomte : First results of charge density study in proteins

16:00 – 16:30 Discussion : High Resolution Perspectives.

4) 17:00-18:30 : Large complexes I

17:00 – 17:30 Curt Davey

The High Resolution Crystal Structure of the Nucleosome Core Particle : Sequence-Dependent DNA-Bending and Plasticity of Histone-DNA Binding.

17:30 – 18:00 Dino Moras

The structure of the Threonyl-tRNA-synthetase complex

18:00 – 18:30 Patrick Cramer

Structure of RNA polymerase II

 

• Evening: Special Dinner.

Saturday

• Morning:

5) 09:00-11:00 : Large complexes. The Ribosome

09:00 – 09:30 Ada Yonath

Ribosome's Function at Close to Atomic Resolution

09:30 – 10:00 Nenad Ban

The complete structure of the large ribosomal subunit at 2.5 Å resolution

10:00–10:30 Marat Yousupov

Localization of tRNAs and mRNA on the structure of a bacterial 70S ribosome at 5.0 A resolution.

10:30–11:00 Ditlev Brodersen

Tackling large molecular assemblies.
The structure of a bacterial 30S ribosomal subunit

 

6) 11:30-12:30 : Crystallography and NMR

11:30–12:00 Analisa Pastore

The structure of titin, a giant muscle protein

12:00 – 12:30 Bruno Kieffer

Solution structure of two fragments of the human transcription factor TFIIh : the RING finger family revisited

 

- Afternoon

7)14:30-15:40 : Large complexes III

14:30–15:00 Claudia Binda

Structure of glutamate synthase, a complex iron-sulphur flavoprotein

15:00 – 15:20 Manfred Baumstark :
Structure of human low-density lipoproteine (LDL) at low resolution : crystallization and data analysis

15:20 – 15:40 Vladimir Yu. Lunin
Structure of human low-density lipoproteine (LDL) at low resolution : Ab initio phasing methods for structure determination

16:00- 17:30 Short communications session (10’+5’ discussion each)

S1) Anthony Adlagatta

Ultra-high resolution tructure of a new polymorphic form of bovine pancreatic trypsin inhibitor

S2) Javier Borge

Vector-search rotation functions in macromolecular crystallography: Foundations

S3) Ossama El-Kabbani

Homology modelling and inhibitor design of human sorbitol dehydrogenase

S4) Christial Jelsch

Refinement of proteins at subatomic resolution.

 

S5)Vladimir V. Lunin

The refinement of the Serratia marcescens endonuclease structure at 1.1 Å Resolution.

 

S6) Carmen Álvarez-Rúa

Vector-search rotation functions in macromolecular crystallography: A new computer program and some practical examples

S7) Piero Temussi

Solution structure of a sweet protein (MNEI)

S8) Martin Walsh

Crystal structure of cyanase

 

- Musical Evening

Sunday

- Morning:

8) 09:00-10:30 : Structural Genomics

09:00 – 09:30 Udo Heinemann

Structural Genomics In Berlin: The Protein Structure Factory Project

09:30 – 10:00 Andrzej Joachimiak

Structural Genomics - Exploring Protein Folding Space

10:00 – 10:30 Discussion

9) 11:00-12:40 : Crystallography and EM

11:00–11:30 Marin Van Heel

Single-particle cryo-EM of biological macromolecules: towards atomic resolution

11:30 – 12:00 Chris Gilmore

Electron Microscopy, Electron Diffraction and Protein Crystallography

12:00 – 12:30 Patrick Schulz

Electron microscopy studies of the TAF_II containing complex TF_IID and TFTC

 

- Leave 14:00 hrs.